Psittacido Herpesvirus 1

Psittacido herpesvirus 1 (PsHV-1) is a DNA virus which has been recognized four genotypes, with different regional distribution. Is causing Pacheco's disease, an acute, highly contagious and often lethal in psittacine birds. It has been suggested a role for the PsHV-1 in tumor development, as they have repeatedly found their genome sequences in mucosal papillomas of parrots. Pacheco's disease may present with nonspecific symptoms such as depression, anorexia, diarrhea and tremors, while other birds do not develop symptoms, becoming chronic carriers of the virus. (2, 4)
As the signs of clinical disease in chickens vary widely and the diagnosis may be complicated further by the different responses to infection in different hosts, clinical signs alone do not have a reliable basis for the diagnosis of Pacheco's disease. Bioingentech can detect the virus Pacheco's disease using the following techniques:

Technique	Reference
Conventional polymerase chain reaction(3)	Tomaszewski et al., 2003(5)
Real-Time polymerase chain reaction(3)	Katoh et al., 2008(1)

Bibliography

Katoh H, Ohya K, Fukushi H. Development of novel real-time PCR assays for detecting DNA virus infections in psittaciform birds. J Virol Methods. 2008 Dec;154(1-2):92-8.
Katoh H, Ogawa H, Ohya K, Fukushi H. A Review of DNA Viral Infections in Psittacine Birds. J Vet Med Sci. 2010 Apr 16.
Sambrook J, Frisch EF, Maniatis T. Molecular Cloning, A laboratory manual, 2a ed. 1990.
Thureen DR, Keeler CL Jr. Psittacid herpesvirus 1 and infectious laryngotracheitis virus: Comparative genome sequence analysis of two avian alphaherpesviruses. J Virol. 2006 Aug;80(16):7863-72.
Tomaszewski EK, Kaleta EF, Phalen DN. Molecular phylogeny of the psittacid herpesviruses causing Pacheco's disease: correlation of genotype with phenotypic expression. J Virol. 2003 Oct;77(20):11260-7.